113 arrest warrants, according to Turkish officials, have been issued in relation to the building of the structures that were destroyed by the earthquake on Monday.
At least 12 people, including building contractors, have already been detained by Turkish police.
In the meantime, some rescue operations have been hampered by unrest in southern Turkey.
More than 8,000 deaths in Turkey and Syria have now been officially confirmed.
More arrests are anticipated; however, many will view the move as an effort to shift the burden of responsibility for the catastrophe.
Due to widespread corruption and government policies, experts have long warned that many new buildings in Turkey are unsafe.
The purpose of those policies was to promote a construction boom, including in earthquake-prone areas, by allowing so-called amnesties for contractors who flouted building regulations.
Numerous buildings collapsed during the earthquake, raising concerns about whether human error contributed to the severity of the natural disaster.
The president's future is uncertain as elections approach after 20 years in office.
Mr. Erdogan has acknowledged that the response had issues, but on one occasion when he visited a disaster area, he seemed to put the blame on fate. Such incidents have always occurred, he said. It is a component of destiny's plan.
The situation is getting worse on the sixth day following the earthquake.
Due to clashes between unnamed groups in the province of Hatay, German rescuers and the Austrian army halted search operations on Saturday. As food supplies become scarcer, one rescuer predicted that security would deteriorate.
Austrian Lieutenant Colonel Pierre Kugelweis claimed that factions in Turkey were becoming more aggressive. The likelihood of saving a life is not reasonably correlated with the safety risk.
Under the protection of the Turkish army, the search for survivors resumed.
Millions of people are homeless throughout southern Turkey and northern Syria, and nightly lows below zero continue.
More than 800,000 people aren't getting enough to eat, and the UN's local aid organization has warned that the final death toll from the earthquake will probably double.
The death toll in Syria now exceeds 3,500, but since Friday, no new figures have been released.
Despite some amazing rescues, there are now fewer survivors that can be found.
A five-person family from Turkey's Gaziantep province and a seven-year-old Hatay girl who spent 132 hours buried under the rubble were among those rescued on Saturday.
The head of UN relief operations, who was in the Turkish province of Kahramanmaras on Saturday, described the earthquake as the "worst event in this region in 100 years.".
Martin Griffiths, who was in Turkey reporting for the BBC, said, "I think it's the worst natural disaster I've ever seen and it's also the most extraordinary international response.".
In the wake of the disaster, Mr. Griffiths has urged regional politics to be set aside, and there are some indications that this is taking place.
In order to allow aid to pass, the Turkish-Armenian border crossing reopened on Saturday for the first time in 35 years.
