Goal, an Irish aid organization, has confirmed that 27 of its employees died in the earthquake in Turkey and Syria.
One Turkish citizen and 26 Syrians were among the victims, according to the charity, but unspecified numbers of other Goal aid workers are still missing.
Siobhan Walsh, the CEO of Goal, stated that "the scale of loss is far beyond anything we could have ever imagined.".
The disaster is known to have claimed the lives of over 23,700 people in total.
Goal team members working in Turkey and Syria, according to Ms. Walsh, had a "profoundly difficult week.".
After visiting India and being moved to tears by the plight of street children, Irish journalist John O'Shea founded Goal in 1977.
With 3,500 employees working in 14 countries, it is now a global organization.
With more than 900 employees currently employed in Syria's north-west, Goal has been operating there since 2012.
In order to assist refugees, it sent staff to Turkey in 2016, and it currently employs more than 250 people in the provinces of the southeast.
The charity stated in a statement that safeguarding each and every employee's safety has been a top priority since last Monday.
"However, this has presented significant difficulties given the immediate movement of staff to find shelter and safety following the earthquake, the loss of electricity and power for telecommunications, damaged and impassable roads, and the utter geography of destruction and desolation across the vast region.
Micheál Martin, the Tánaiste and minister for foreign affairs of Ireland, expressed his "deep sorrow" upon learning of the significant loss of life among Goal staff as a result of the tragic earthquake on Monday.